Tryptase (Mast Cell Marker) (TPSAB1/1961), CF647 conjugate, 0.1mg/mL

Catalog number BNC471961-100

Price for BNC471961-100

Size / count 1x 100 µL

About this product

Tryptases comprise a family of trypsin-like serine proteases (peptidase family S1) . Tryptases are stored in mast cell secretory granules and basophils. Mast cells are connective tissue cells derived from blood-forming tissues that line arterial walls and secrete substances, which mediate inflammatory and immune responses. Tryptases are released into the extracellular environment and are resistant to all known endogenous proteinase inhibitors. This antibody reacts with mast cells distributed in skin, synovium, lung, and heart. This antibody does not bind with any other cell type. Human mast cell tryptase is considered to be an important marker of mast cell activation and is an important mediator of inflammation. Mastocytosis is a term collectively used for a group of disorders in which there is abnormal accumulation of mast cells in one or multiple organs. Anti-tryptase, combined with anti-CD2, anti-CD25, and anti-CD117, can be useful in identifying reactive mast cell hyperplasia, myelogenous neoplasms, mast cell leukemia, and mastocytosis.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC471961-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Lung Tryptase; Mast cell alpha II Tryptase; Mast cell beta I Tryptase; Mast cell protease 7; Mast cell protease II; MCP7; Pituitary Tryptase; Skin Tryptase; TPS1; TPSAB1; TPSB1; Tryptase 1; Tryptase alpha 1; Tryptase skin
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TPSAB1
Gene ID: 7177
NCBI Gene ID: 405479
UniProt: Q15661
Swiss Prot: Q15661
Host: Mouse
Species Reactivity: Human
Reactivity: Tryptase
Immunogen: Recombinant human Tryptase protein fragment (around aa 115-233) (Exact sequence is proprietary)
Target Antigen: Tryptase
Clonality: Monoclonal
Clone: TPSAB1/1961
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Immunology, Inflammation
Positive Control: Skin or Tonsil
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 31-36 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for Tryptase (Mast Cell Marker) (TPSAB1/1961), CF647 conjugate, 0.1mg/mL?

The catalog number for Tryptase (Mast Cell Marker) (TPSAB1/1961), CF647 conjugate, 0.1mg/mL is BNC471961-100.

What sizes are available for Tryptase (Mast Cell Marker) (TPSAB1/1961), CF647 conjugate, 0.1mg/mL?

Tryptase (Mast Cell Marker) (TPSAB1/1961), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Tryptase (Mast Cell Marker) (TPSAB1/1961), CF647 conjugate, 0.1mg/mL in stock?

Tryptase (Mast Cell Marker) (TPSAB1/1961), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Tryptase (Mast Cell Marker) (TPSAB1/1961), CF647 conjugate, 0.1mg/mL?

Tryptase (Mast Cell Marker) (TPSAB1/1961), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Tryptase (Mast Cell Marker) (TPSAB1/1961), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Tryptase (Mast Cell Marker) (TPSAB1/1961), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Tryptase (Mast Cell Marker) (TPSAB1/1961), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Tryptase (Mast Cell Marker) (TPSAB1/1961), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02ae061270361e108cee/msds/bnc471961-100.pdf.

What is Tryptase (Mast Cell Marker) (TPSAB1/1961), CF647 conjugate, 0.1mg/mL used for?

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.