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Product details
Catalog number BNC812748-500
Price for BNC812748-500
Size / count 1x 500 µL
This antibody recognizes a protein of 42 kDa, which is identified as Alpha-methylacyl-CoA Racemase (AMACR), also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and betbeta-oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells) . Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium) . AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for AMACR / p504S (Prostate Cancer Marker) (AMACR/2748R), CF680R conjugate, 0.1mg/mL is BNC812748-500.
AMACR / p504S (Prostate Cancer Marker) (AMACR/2748R), CF680R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
AMACR / p504S (Prostate Cancer Marker) (AMACR/2748R), CF680R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
AMACR / p504S (Prostate Cancer Marker) (AMACR/2748R), CF680R conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for AMACR / p504S (Prostate Cancer Marker) (AMACR/2748R), CF680R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for AMACR / p504S (Prostate Cancer Marker) (AMACR/2748R), CF680R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
This antibody recognizes a protein of 42 kDa, which is identified as Alpha-methylacyl-CoA Racemase (AMACR), also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and betbeta-oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in
We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.
Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.
Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.
