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Product details

p18 INK4c Recombinant Rabbit Monoclonal Antibody [JE36-09]

Catalog number HA721960

Price for HA721960

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Size / count 100 µL

About this product

Cyclin-dependent kinase 4 inhibitor C is an enzyme that in humans is encoded by the CDKN2C gene. The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.

Specifications

Catalog number
HA721960
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
CDK6 inhibitor p18 antibody CDKN 2C antibody CDKN 6 antibody Cdkn2c antibody CDKN6 antibody CDN2C_HUMAN antibody Cyclin dependent inhibitor antibody Cyclin dependent kinase 4 inhibitor C antibody Cyclin dependent kinase 6 inhibitor antibody Cyclin dependent kinase 6 inhibitor p18 antibody Cyclin dependent kinase inhibitor 2C (p18 inhibits CDK4) antibody Cyclin dependent kinase inhibitor 2C antibody Cyclin-dependent kinase 4 inhibitor C antibody Cyclin-dependent kinase 6 inhibitor antibody INK4C antibody OTTHUMP00000046546 antibody p18 antibody p18 inhibits CDK4 antibody p18 INK4c antibody p18 INK6 antibody p18-INK4c antibody p18-INK6 antibody
Abbreviation
CDKN2C, CDKN6
Swiss Prot
P42773 Human, Q60772 Mouse,
Cellular Locus
Cytoplasm, cytosol, nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human p18 INK4c aa 1-150 / 168.
Isotype
IgG
Clone
JE36-09
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
HeLa cell lysate, 293T cell lysate, MCF7 cell lysate, A549 cell lysate, mouse skeletal muscle tissue lysate, rat skeletal muscle tissue lysate, human skeletal muscle tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:500
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 18 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for p18 INK4c Recombinant Rabbit Monoclonal Antibody [JE36-09]?

The catalog number for p18 INK4c Recombinant Rabbit Monoclonal Antibody [JE36-09] is HA721960.

What sizes are available for p18 INK4c Recombinant Rabbit Monoclonal Antibody [JE36-09]?

p18 INK4c Recombinant Rabbit Monoclonal Antibody [JE36-09] is available in the following size(s): 100 µL.

Is p18 INK4c Recombinant Rabbit Monoclonal Antibody [JE36-09] in stock?

p18 INK4c Recombinant Rabbit Monoclonal Antibody [JE36-09] is currently made to order / not held in immediate stock. Contact us for lead time.

What is p18 INK4c Recombinant Rabbit Monoclonal Antibody [JE36-09] used for?

Cyclin-dependent kinase 4 inhibitor C is an enzyme that in humans is encoded by the CDKN2C gene. The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kin

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

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