TGF beta Receptor II Recombinant Rabbit Monoclonal Antibody [JE59-90]

Catalog number HA721480

Price for HA721480

Size / count 100 µL

About this product

Transforming growth factor, beta receptor II (70/80kDa) is a TGF beta receptor. TGFBR2 is its human gene. It is a tumor suppressor gene. This gene encodes a member of the serine/threonine protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler–Weber–Rendu syndrome, and the development of various types of tumors. At least 73 disease-causing mutations in this gene have been discovered. Alternatively spliced transcript variants encoding different isoforms have been characterized.

Specifications

Catalog number: HA721480
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: AAT3 antibody FAA3 antibody LDS1B antibody LDS2 antibody LDS2B antibody MFS2 antibody RIIC antibody TAAD2 antibody TbetaR II antibody TbetaR-II antibody TGF beta receptor type 2 antibody TGF beta receptor type II antibody TGF beta receptor type IIB antibody TGF beta type II receptor antibody TGF-beta receptor type II antibody TGF-beta receptor type-2 antibody TGF-beta type II receptor antibody TGF-beta-R2 antibody TGFB R2 antibody TGFbeta - RII antibody TGFbeta RII antibody Tgfbr2 antibody TGFR-2 antibody TGFR2_HUMAN antibody Transforming growth factor beta receptor II antibody Transforming growth factor beta receptor type II antibody Transforming growth factor beta receptor type IIC antibody Transforming growth factor, beta receptor II (70/80kDa) antibody transforming growth factor, beta receptor II alpha antibody transforming growth factor, beta receptor II beta antibody transforming growth factor, beta receptor II delta antibody transforming growth factor, beta receptor II epsilon antibody transforming growth factor, beta receptor II gamma antibody Transforming growth factor-beta receptor type II antibody
Abbreviation: TGFBR2
Swiss Prot: P37173 Human, P38438 Rat
Cellular Locus: Cell membrane, Membrane raft; Secreted.
Host: Rabbit
Species Reactivity: Human, Rat
Immunogen: Recombinant protein within Human TGF beta Receptor II aa 1-166 / 567.
Isotype: IgG
Clone: JE59-90
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB
Positive Control: A549 cell lysate, rat lung tissue lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 65 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for TGF beta Receptor II Recombinant Rabbit Monoclonal Antibody [JE59-90]?

The catalog number for TGF beta Receptor II Recombinant Rabbit Monoclonal Antibody [JE59-90] is HA721480.

What sizes are available for TGF beta Receptor II Recombinant Rabbit Monoclonal Antibody [JE59-90]?

TGF beta Receptor II Recombinant Rabbit Monoclonal Antibody [JE59-90] is available in the following size(s): 100 µL.

Is TGF beta Receptor II Recombinant Rabbit Monoclonal Antibody [JE59-90] in stock?

TGF beta Receptor II Recombinant Rabbit Monoclonal Antibody [JE59-90] is currently made to order / not held in immediate stock. Contact us for lead time.

What is TGF beta Receptor II Recombinant Rabbit Monoclonal Antibody [JE59-90] used for?

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.