Lamin A/C Monoclonal Antibody — image 1 of 3

Product details

Lamin A/C Monoclonal Antibody

Catalog number AN005340L-01

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Price for AN005340L-01

Size / count 25 µL

Specifications

Catalog number: AN005340L-01
Size / count: 25 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Lamin A/C is also named as LMNA, or LMN1. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. The lack of lamin A/C can be as a novel marker for undifferentiated embryonic stem cells and lamin A/C expression is as an early indicator of differentiation (PMID: 16179429) . Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. This protein has 4 isoforms produced by alternative splicing with the molecular weight of 74 kDa,65 kDa,70 kDa and 64 kDa. This antibody can recognize 4 isoforms of Lamin A/C.
Abbreviation: Lamin A/C
UniProt: P02545
Host: Mouse
Reactivity: Human
Immunogen: Recombinant human Lamin A/C protein expressed by E.coli
Target: Prelamin-A/C; LMNA; LMN1; Lamin A/C
Clonality: Monoclonal
Clone: 4F1
Conjugation: Unconjugated
Applications: WB; IF
Field of Research: Signal Transduction; Tags and Cell Markers; Cancer; Cell Biology; Developmental Biology; Epigenetics and Nuclear Signaling; Biochemicals
Purification: Protein A/G Purification
Concentration: 1 mg/mL
Dilution: WB 1:2000-1:4000; IF 1:500-1:1000
Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH 7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Protected from prolonged exposure to light.
Calculated Molecular Weight: 65 kDa
Observed Molecular Weight: 70,80 kDa
Isotype: IgG1

Frequently Asked Questions

What is the catalog number for Lamin A/C Monoclonal Antibody?

The catalog number for Lamin A/C Monoclonal Antibody is AN005340L.

What sizes are available for Lamin A/C Monoclonal Antibody?

Lamin A/C Monoclonal Antibody is available in the following size(s): 25 µL, 100 µL.

How many pack sizes does Lamin A/C Monoclonal Antibody come in?

Lamin A/C Monoclonal Antibody is available in 2 different pack sizes.

Is Lamin A/C Monoclonal Antibody in stock?

Lamin A/C Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Lamin A/C Monoclonal Antibody?

Lamin A/C Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Lamin A/C Monoclonal Antibody?

Estimated delivery time for Lamin A/C Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Lamin A/C Monoclonal Antibody?

The safety data sheet for Lamin A/C Monoclonal Antibody is available here: https://789.bio/eb/SpeDtS.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.